RA CAPITAL MANAGEMENT, LLC

Former 10% Owner at Satsuma Pharmaceuticals, Inc. · on record since Jun 12, 2023
Former 10% owners and Director at DICE Therapeutics, Inc. · on record since Aug 9, 2023
Director at Black Diamond Therapeutics, Inc. · on record since Jul 7, 2023
10% owner at ARS Pharmaceuticals, Inc. · on record since Mar 27, 2024
10% owner at LOT78, INC. · on record since Mar 27, 2024
10% owner at LIPID SCIENCES INC/ · on record since Dec 29, 2006
Director at Cidara Therapeutics, Inc. · on record since Apr 30, 2024
Former 10% Owner at iTeos Therapeutics, Inc. · on record since May 14, 2024
10% owner at ARADIGM CORP · on record since Mar 28, 2007
Director at Septerna, Inc. · on record since Oct 30, 2024
10% owner at Septerna, Inc. · on record since Oct 30, 2024
10% owner at 4D Molecular Therapeutics, Inc. · on record since Nov 25, 2024
10% owner at CURIS INC · on record since Aug 15, 2007
Director at Sionna Therapeutics, Inc. · on record since Feb 10, 2025
10% owner at Sionna Therapeutics, Inc. · on record since Feb 10, 2025
10% owner at Cidara Therapeutics, Inc. · on record since Jun 30, 2025
10% owner at Prelude Therapeutics Inc · on record since Apr 28, 2026
Director at Evommune, Inc. · on record since Nov 12, 2025
10% owner at · on record since Nov 12, 2025
10% owner at · on record since Jun 27, 2008
10% owner at · on record since Sep 26, 2008
Director at · on record since Feb 11, 2026
10% owner at · on record since Feb 11, 2026
10% owner at · on record since Jul 17, 2026
Director at · on record since Jul 22, 2026
10% owner at · on record since Jul 22, 2026
Director at · on record since Apr 6, 2026
10% owner at · on record since Apr 6, 2026
10% owner at · on record since Apr 13, 2026
Director at · on record since Oct 31, 2016
Director at · on record since Apr 23, 2026
10% owner at · on record since Apr 23, 2026
Director at · on record since Sep 17, 2019
10% owner at · on record since Sep 17, 2019
Director at · on record since Apr 30, 2026
Director at · on record since Apr 29, 2026
10% owner at · on record since Apr 29, 2026
10% owner at · on record since Apr 30, 2026
10% owner at · on record since May 12, 2026
Director at · on record since May 13, 2026
10% owner at · on record since May 13, 2026
10% owner at · on record since Jun 5, 2026
10% owner at · on record since Oct 25, 2016
Director at · on record since Nov 23, 2016
10% owner at · on record since May 1, 2013
10% owner at · on record since Oct 4, 2013
Director at · on record since Jun 1, 2026
10% owner at · on record since Jun 1, 2026
Fmr 10% Owner - See Fn (1)-(5) at · on record since Jan 13, 2014
Director at · on record since Jun 5, 2026
Director at · on record since Jun 9, 2026
Director at · on record since Jun 10, 2026
10% owner at · on record since Jun 10, 2026
Director at · on record since Jun 11, 2026
10% owner at · on record since Jun 11, 2026
Director at · on record since Jun 12, 2026
Director at · on record since Jun 15, 2026
10% owner at · on record since Jun 15, 2026
10% owner at · on record since Jun 15, 2026
Former 10% Owner. See FN(1)(6) at · on record since Jan 20, 2015
10% owner at · on record since Feb 18, 2015
Former 10% Owner. at · on record since Feb 18, 2015
10% owner at · on record since Oct 30, 2015
Director at · on record since Nov 18, 2015
10% owner at · on record since Nov 18, 2015
Fmr 10% Owner See Footnote (2) at · on record since May 24, 2017
Director at · on record since May 16, 2017
10% owner at · on record since May 16, 2017
Director at · on record since Apr 13, 2017
10% owner at · on record since Apr 13, 2017
Director at · on record since Jul 26, 2017
10% owner at · on record since Jul 19, 2017
10% owner at · on record since Nov 21, 2017
10% owner at · on record since Oct 16, 2017
Director at · on record since Apr 5, 2021
Director at · on record since Apr 5, 2021
Director at · on record since Jun 22, 2018
10% owner at · on record since Sep 26, 2018
10% owner at · on record since Oct 25, 2018
10% owner at · on record since Dec 13, 2018
Former 10% Owner at · on record since Oct 3, 2018
10% owner at · on record since Oct 18, 2019
Director at · on record since Nov 13, 2019
10% owner at · on record since Nov 13, 2019
10% owner at · on record since Nov 4, 2019
10% owner at · on record since Mar 5, 2020
10% owner at · on record since Jun 25, 2020
10% owner at · on record since Jun 24, 2020
10% owner at · on record since Jun 18, 2020
10% owner at · on record since May 7, 2020
10% owner at · on record since Sep 29, 2020
10% owner at · on record since Jul 29, 2020
10% owner at · on record since Jul 28, 2020
10% owner at · on record since Aug 24, 2020
10% owner at · on record since Sep 23, 2020
10% owner at · on record since Jul 22, 2020
Director at · on record since Jul 29, 2021
10% owner at · on record since Dec 17, 2020
Director at · on record since Dec 15, 2020
10% owner at · on record since Dec 15, 2020
10% owner at · on record since Nov 6, 2020
Former 10% Owner at · on record since Dec 4, 2020
10% owner at · on record since Oct 2, 2020
10% owner at · on record since Dec 2, 2020
Director at · on record since Feb 11, 2021
Director at · on record since Jun 30, 2021
Director at · on record since Jun 29, 2021
10% owner at · on record since Jun 29, 2021
Director at · on record since Apr 29, 2021
Director at · on record since Jul 28, 2021
10% owner at · on record since Jul 28, 2021
Director at · on record since Sep 20, 2021
10% owner at · on record since Sep 20, 2021
10% owner at · on record since Aug 13, 2021
10% owner at · on record since Mar 31, 2022
10% owner at · on record since Mar 16, 2022
Director at · on record since May 12, 2022
10% owner at · on record since May 12, 2022
10% owner at · on record since Aug 26, 2022
Former 10% owner at · on record since Feb 27, 2023
Director at · on record since Feb 16, 2023
10% owner at · on record since Feb 13, 2023
10% owner at · on record since Mar 17, 2020
Director at · on record since Nov 10, 2022
10% owner at · on record since Jun 12, 2026

Insider trading activity of RA CAPITAL MANAGEMENT, LLC

Transactions on record: 420; since Jun 13, 2008

Open-market buys: 152; $1.2B

Open-market sells: 116; $251M

Companies traded: 53; last filing Sep 30, 2026

Figures computed from official regulatory filings — .

Companies where RA CAPITAL MANAGEMENT, LLC has traded

42 tx · $262.8M · Oct 5, 2026
11 tx · $20.2M · Sep 30, 2026
43 tx · $47.6M · Sep 21, 2026
7 tx · $201.7M · Sep 17, 2026
22 tx · $117.5M · Sep 14, 2026
3 tx · $63.5M · Aug 14, 2026
2 tx · Jul 31, 2026
15 tx · $430.7M · Jul 22, 2026
7 tx · $52.6M · Jul 22, 2026
5 tx · $36.5M · Jun 26, 2026
21 tx · $963.9K · Jun 22, 2026
4 tx · $7M · Jun 22, 2026
1 tx · Jun 22, 2026
25 tx · $55.5M · Jun 17, 2026

Track record of RA CAPITAL MANAGEMENT, LLC

Statistical track record

Free account

Open-market buys: 157

Last buy: Sep 15, 2026

Win rates, median returns and the proven-insider analysis come with a free account.

Transaction history of RA CAPITAL MANAGEMENT, LLC

Co-insiders of RA CAPITAL MANAGEMENT, LLC

This page republishes public regulatory disclosures.

Company	Filed	Type	Qty	Price	Value · USD	Signals	Src
Vor Biopharma Inc.Listing on record	Oct 5, 2026	ExerciseD (derivative)	-500	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Vor Biopharma Inc.Listing on record	Oct 5, 2026	Exercise	500	12.80 USD	$6.4K		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	Exercise	10,000	3.00 USD	$30K		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	ExerciseD (derivative)	-10,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	ExerciseD (derivative)	-10,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	Exercise	40,000	1.29 USD	$51.6K		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	Exercise	10,000	7.89 USD	$78.9K		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	ExerciseD (derivative)	-10,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	ExerciseD (derivative)	-40,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	Exercise	10,000	3.46 USD	$34.6K		SEC
Sionna Therapeutics, Inc.Listing unverified	Sep 21, 2026	Sell	-3,415,011	6.32 USD	$21.6M		SEC
Sionna Therapeutics, Inc.Listing unverified	Sep 21, 2026	Sell	-33,800	7.46 USD	$252.1K		SEC
Tyra Biosciences, Inc.Listing on record	Sep 17, 2026	BuyD (derivative)	9,078,529	22.03 USD	$200M	Unusual size	SEC
Artiva Biotherapeutics, Inc.Listing unverified	Sep 14, 2026	AwardD (derivative)	16,250	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Artiva Biotherapeutics, Inc.Listing unverified	Sep 8, 2026	AwardD (derivative)	13,750	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Vor Biopharma Inc.Listing on record	Aug 26, 2026	Exercise	1,500	3.74 USD	$5.6K		SEC
Vor Biopharma Inc.Listing on record	Aug 26, 2026	ExerciseD (derivative)	-1,500	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Septerna, Inc.Listing unverified	Aug 14, 2026	Sell	-746,500	42.50 USD	$31.7M	Unusual size	SEC
Septerna, Inc.Listing unverified	Aug 14, 2026	Sell	-746,500	42.50 USD	$31.7M	Unusual size	SEC
Artiva Biotherapeutics, Inc.Listing unverified	Jul 31, 2026	Buy	20,824	9.99 USD	$208K	conv 20	SEC
Inhibikase Therapeutics, Inc.Listing on record	Jul 31, 2026	OtherD (derivative)	18,030,000	—	n/a (No price was disclosed in the filing)		SEC
Artiva Biotherapeutics, Inc.Listing unverified	Jul 31, 2026	Buy	24,944	9.93 USD	$247.7K	conv 19	SEC
Inhibikase Therapeutics, Inc.Listing on record	Jul 31, 2026	Other	-18,030,000	—	n/a (No price was disclosed in the filing)		SEC
Artiva Biotherapeutics, Inc.Listing unverified	Jul 28, 2026	Buy	41,319	9.99 USD	$412.8K	conv 19	SEC
Artiva Biotherapeutics, Inc.Listing unverified	Jul 23, 2026	Buy	120,582	9.55 USD	$1.2M	conv 20	SEC

Company	Filed	Type	Qty	Price	Value · USD	Signals	Src
Vor Biopharma Inc.Listing on record	Oct 5, 2026	ExerciseD (derivative)	-500	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Vor Biopharma Inc.Listing on record	Oct 5, 2026	Exercise	500	12.80 USD	$6.4K		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	Exercise	10,000	3.00 USD	$30K		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	ExerciseD (derivative)	-10,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	ExerciseD (derivative)	-10,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	Exercise	40,000	1.29 USD	$51.6K		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	Exercise	10,000	7.89 USD	$78.9K		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	ExerciseD (derivative)	-10,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	ExerciseD (derivative)	-40,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Climb Bio, Inc.Listing on record	Sep 30, 2026	Exercise	10,000	3.46 USD	$34.6K		SEC
Sionna Therapeutics, Inc.Listing unverified	Sep 21, 2026	Sell	-3,415,011	6.32 USD	$21.6M		SEC
Sionna Therapeutics, Inc.Listing unverified	Sep 21, 2026	Sell	-33,800	7.46 USD	$252.1K		SEC
Tyra Biosciences, Inc.Listing on record	Sep 17, 2026	BuyD (derivative)	9,078,529	22.03 USD	$200M	Unusual size	SEC
Artiva Biotherapeutics, Inc.Listing unverified	Sep 14, 2026	AwardD (derivative)	16,250	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Artiva Biotherapeutics, Inc.Listing unverified	Sep 8, 2026	AwardD (derivative)	13,750	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Vor Biopharma Inc.Listing on record	Aug 26, 2026	Exercise	1,500	3.74 USD	$5.6K		SEC
Vor Biopharma Inc.Listing on record	Aug 26, 2026	ExerciseD (derivative)	-1,500	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Septerna, Inc.Listing unverified	Aug 14, 2026	Sell	-746,500	42.50 USD	$31.7M	Unusual size	SEC
Septerna, Inc.Listing unverified	Aug 14, 2026	Sell	-746,500	42.50 USD	$31.7M	Unusual size	SEC
Artiva Biotherapeutics, Inc.Listing unverified	Jul 31, 2026	Buy	20,824	9.99 USD	$208K	conv 20	SEC
Inhibikase Therapeutics, Inc.Listing on record	Jul 31, 2026	OtherD (derivative)	18,030,000	—	n/a (No price was disclosed in the filing)		SEC
Artiva Biotherapeutics, Inc.Listing unverified	Jul 31, 2026	Buy	24,944	9.93 USD	$247.7K	conv 19	SEC
Inhibikase Therapeutics, Inc.Listing on record	Jul 31, 2026	Other	-18,030,000	—	n/a (No price was disclosed in the filing)		SEC
Artiva Biotherapeutics, Inc.Listing unverified	Jul 28, 2026	Buy	41,319	9.99 USD	$412.8K	conv 19	SEC
Artiva Biotherapeutics, Inc.Listing unverified	Jul 23, 2026	Buy	120,582	9.55 USD	$1.2M	conv 20	SEC