PERCEPTIVE ADVISORS LLC

• 10% owner at SOLENO THERAPEUTICS INC · on record since May 26, 2023
• 10% owner at CHEMBIO DIAGNOSTICS, INC. · on record since Apr 25, 2023
• Former 10% Owner at CHEMBIO DIAGNOSTICS, INC. · on record since May 1, 2023
• 10% owner at INDEVUS PHARMACEUTICALS INC · on record since Jun 29, 2006
• Former 10% Owner at CARGO Therapeutics, Inc. · on record since Nov 14, 2023
• 10% owner at CARGO Therapeutics, Inc. · on record since Nov 9, 2023
• 10% owner at FELAFEL CORP · on record since Jun 27, 2024
• 10% owner at Orchestra BioMed Holdings, Inc. · on record since Jul 17, 2024
• Director at Adagio Medical Holdings, Inc. · on record since Aug 1, 2024
• 10% owner at Adagio Medical Holdings, Inc. · on record since Aug 1, 2024
• 10% owner at Rain Enhancement Technologies Holdco, Inc. · on record since Apr 27, 2021
• 10% owner at BIOENVISION INC · on record since Aug 22, 2007
• 10% owner at XTL BIOPHARMACEUTICALS LTD · on record since Dec 31, 2007
• 10% owner at MACROCHEM CORP · on record since Dec 28, 2007
• 10% owner at OPTIMER PHARMACEUTICALS INC · on record since Dec 27, 2007
• 10% owner at PENWEST PHARMACEUTICALS CO · on record since Jan 31, 2008
• Director at Immatics N.V. · on record since Mar 18, 2026
• Director at Kardigan, Inc. · on record since Jun 18, 2026
• Director at ARYA SCIENCES ACQUISITION CORP. · on record since May 24, 2021
• Managing Member at CYPRESS BIOSCIENCE INC · on record since Aug 8, 2003
• 10% owner at BIOSANTE PHARMACEUTICALS INC · on record since Aug 13, 2003
• Managing Member at BIOSANTE PHARMACEUTICALS INC · on record since Aug 13, 2003
• 10% owner at MIRAVANT MEDICAL TECHNOLOGIES · on record since Jun 8, 2004
• 10% owner at ZONAGEN INC · on record since Feb 28, 2011
• 10% owner at TRIMERIS INC · on record since Jul 29, 2011
• 10% owner at AP PHARMA INC /DE/ · on record since Jul 7, 2011
• Director at MeiraGTx Holdings plc · on record since Apr 23, 2026
• 10% owner at MeiraGTx Holdings plc · on record since Apr 23, 2026
• 10% owner at ACELRX PHARMACEUTICALS INC · on record since Dec 13, 2012
• 10% owner at Aegerion Pharmaceuticals, Inc. · on record since Dec 5, 2012
• 10% owner at ANTARES PHARMA INC · on record since Feb 12, 2004
• 10% owner at AMICUS THERAPEUTICS INC · on record since May 30, 2014
• Director at Solid Biosciences Inc. · on record since Jun 11, 2026
• 10% owner at Solid Biosciences Inc. · on record since Jun 11, 2026
• 10% owner at PAULSON CAPITAL CORP · on record since Mar 11, 2015
• 10% owner at Aldeyra Therapeutics, Inc. · on record since Oct 28, 2015
• Former Director at Nautilus Biotechnology, Inc. · on record since Jun 11, 2021
• 10% owner at Versartis, Inc. · on record since Sep 28, 2016
• No longer a 10% Owner. at AMICUS THERAPEUTICS INC · on record since Aug 26, 2016
• 10% owner at CORILLIAN CORP · on record since May 25, 2017
• 10% owner at ZOGENIX, INC. · on record since May 18, 2017
• 10% owner at Quotient Ltd · on record since Oct 26, 2017
• 10% owner at Global Blood Therapeutics, Inc. · on record since Dec 19, 2017
• 10% owner at LA JOLLA PHARMACEUTICAL CO · on record since Dec 18, 2017
• 10% owner at R&R ACQUISITION VI, INC · on record since Nov 15, 2017
• 10% owner at Biodel Inc · on record since Dec 4, 2017
• 10% owner at AGILE THERAPEUTICS INC · on record since Mar 28, 2018
• 10% owner at Motus GI Holdings, Inc. · on record since Feb 21, 2018
• 10% owner at Kadmon Holdings, LLC · on record since Jun 22, 2018
• 10% owner at Dova Pharmaceuticals, Inc. · on record since Jun 13, 2018
• Director at Crinetics Pharmaceuticals, Inc. · on record since Aug 27, 2018
• 10% owner at Crinetics Pharmaceuticals, Inc. · on record since Aug 27, 2018
• Former 10% Owner at AGILE THERAPEUTICS INC · on record since Jul 26, 2018
• Former 10% Owner at Global Blood Therapeutics, Inc. · on record since Jul 25, 2018
• 10% owner at Verrica Pharmaceuticals Inc. · on record since Aug 1, 2018
• 10% owner at Athenex, Inc. · on record since Jun 20, 2019
• 10% owner at Foamix Pharmaceuticals Ltd. · on record since Aug 6, 2019
• Former 10% owner at Kadmon Holdings, LLC · on record since Nov 18, 2019
• Director at Lyra Therapeutics, Inc. · on record since Apr 30, 2020
• 10% owner at Lyra Therapeutics, Inc. · on record since Apr 30, 2020
• 10% owner at LEAP THERAPEUTICS, INC. · on record since Jun 24, 2020
• 10% owner at VYNE Therapeutics Inc. · on record since Jun 11, 2020
• 10% owner at LeonaBio, Inc. · on record since Sep 22, 2020
• Director at Ceres, Inc. · on record since Oct 29, 2020
• Director at ARYA Sciences Acquisition Corp II · on record since Oct 22, 2020
• Director at LeonaBio, Inc. · on record since Jan 27, 2021
• 10% owner at SCYNEXIS INC · on record since Jan 26, 2021
• 10% owner at Ignyta, Inc. · on record since Mar 16, 2021
• Director at Landos Biopharma, Inc. · on record since Feb 9, 2021
• 10% owner at Landos Biopharma, Inc. · on record since Feb 9, 2021
• Director at CATABASIS PHARMACEUTICALS INC · on record since Feb 3, 2021
• 10% owner at CATABASIS PHARMACEUTICALS INC · on record since Feb 3, 2021
• Director at LianBio · on record since Oct 29, 2021
• 10% owner at LianBio · on record since Oct 29, 2021
• 10% owner at ISCO INTERNATIONAL INC · on record since Oct 14, 2021
• Director at Nautilus Biotechnology, Inc. · on record since Dec 10, 2021
• 10% owner at Nautilus Biotechnology, Inc. · on record since Jun 17, 2022
• 10% owner at Acrivon Therapeutics, Inc. · on record since Nov 18, 2022