RA Capital Nexus Fund II, L.P.

Former 10% owners and Director at DICE Therapeutics, Inc. · on record since Aug 9, 2023
10% owner at LOT78, INC. · on record since Mar 27, 2024
10% owner at LENZ Therapeutics, Inc. · on record since Mar 25, 2024
Director at Werewolf Therapeutics, Inc. · on record since May 24, 2024
10% owner at Werewolf Therapeutics, Inc. · on record since May 24, 2024
Director at Freenome, Inc. · on record since Jul 22, 2026
Director at Acrivon Therapeutics, Inc. · on record since Apr 23, 2026
Director at Climb Bio, Inc. · on record since Apr 29, 2026
Director at Hemab Therapeutics Holdings, Inc. · on record since Apr 30, 2026
Director at Acumen Pharmaceuticals, Inc. · on record since Jun 5, 2026
Director at LENZ Therapeutics, Inc. · on record since Jun 15, 2026
Director at Icosavax, Inc. · on record since Jul 28, 2021
10% owner at Icosavax, Inc. · on record since Jul 28, 2021
Director at Cytek Biosciences, Inc. · on record since Jul 29, 2021
Director at DICE Therapeutics, Inc. · on record since Sep 20, 2021
10% owner at DICE Therapeutics, Inc. · on record since Sep 20, 2021
10% owner at Climb Bio, Inc. · on record since Aug 16, 2021
10% owner at Acumen Pharmaceuticals, Inc. · on record since Jun 21, 2022
Director at · on record since May 12, 2022
10% owner at · on record since May 12, 2022
10% owner at · on record since Nov 21, 2022
Director at · on record since Nov 10, 2022
10% owner at · on record since Mar 31, 2022
Director at · on record since Jun 12, 2026

Insider trading activity of RA Capital Nexus Fund II, L.P.

Transactions on record: 43; since Aug 16, 2021

Open-market buys: 19; $98.8M

Open-market sells: 0

Companies traded: 9; last filing May 14, 2025

Figures computed from official regulatory filings — .

Companies where RA Capital Nexus Fund II, L.P. has traded

3 tx · $487.2K · May 14, 2025
1 tx · Jun 21, 2024
9 tx · $15M · Mar 25, 2024
5 tx · $16.8M · Aug 22, 2023
3 tx · $12.4M · Jul 21, 2023
1 tx · Jun 13, 2023
3 tx · $14.8M · Mar 30, 2023
15 tx · $40M · Jun 1, 2022
3 tx · $5.6M · Feb 25, 2022

Track record of RA Capital Nexus Fund II, L.P.

Statistical track record

Free account

Open-market buys: 20

Last buy: May 14, 2025

Win rates, median returns and the proven-insider analysis come with a free account.

Transaction history of RA Capital Nexus Fund II, L.P.

Co-insiders of RA Capital Nexus Fund II, L.P.

This page republishes public regulatory disclosures.

Company	Filed	Type	Qty	Price	Value · USD	Signals	Src
Werewolf Therapeutics, Inc.Listing on record	May 14, 2025	Buy	162,539	0.98 USD	$159.3K	conv 30	SEC
Werewolf Therapeutics, Inc.Listing on record	May 14, 2025	Buy	320,913	0.86 USD	$276K	conv 42First in 12mo	SEC
Werewolf Therapeutics, Inc.Listing on record	May 14, 2025	Buy	52,974	0.98 USD	$51.9K	conv 29	SEC
PepGen Inc.Listing on record	Jun 21, 2024	AwardD (derivative)	13,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	Award	164,729	—	n/a (No price was disclosed in the filing)		SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	AwardD (derivative)	10,580	—	n/a (No price was disclosed in the filing)		SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	Award	694,755	—	n/a (No price was disclosed in the filing)		SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	Buy	933,038	15.03 USD	$14M	conv 44	SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	AwardD (derivative)	54,582	—	n/a (No price was disclosed in the filing)		SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	AwardD (derivative)	27,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	Buy	64,971	15.03 USD	$976.5K	conv 30	SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	AwardD (derivative)	5,371	—	n/a (No price was disclosed in the filing)		SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	Award	2,386,301	—	n/a (No price was disclosed in the filing)		SEC
AN2 Therapeutics, Inc.Listing on record	Aug 22, 2023	Buy	1,777,778	9.00 USD	$16M	conv 41	SEC
Janux Therapeutics, Inc.Listing on record	Jul 21, 2023	Buy	495,008	12.46 USD	$6.2M	conv 35	SEC
Janux Therapeutics, Inc.Listing on record	Jul 21, 2023	BuyD (derivative)	503,226	12.46 USD	$6.3M		SEC
Janux Therapeutics, Inc.Listing on record	Jun 16, 2023	AwardD (derivative)	12,500	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Acumen Pharmaceuticals, Inc.Listing on record	Jun 13, 2023	AwardD (derivative)	-25,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
DICE Therapeutics, Inc.Listing unverified	Mar 30, 2023	Buy	195,997	28.74 USD	$5.6M	conv 21	SEC
DICE Therapeutics, Inc.Listing unverified	Mar 30, 2023	Buy	66,369	29.38 USD	$1.9M	conv 20	SEC
DICE Therapeutics, Inc.Listing unverified	Mar 30, 2023	Buy	246,779	29.24 USD	$7.2M	conv 29	SEC
AN2 Therapeutics, Inc.Listing on record	Jul 28, 2022	Buy	14,938	7.71 USD	$115.2K	conv 21	SEC
AN2 Therapeutics, Inc.Listing on record	Jul 28, 2022	Buy	8,281	7.91 USD	$65.5K	conv 19	SEC
AN2 Therapeutics, Inc.Listing on record	Jun 15, 2022	Buy	61,424	7.97 USD	$489.5K	conv 25Cluster	SEC
AN2 Therapeutics, Inc.Listing on record	Jun 15, 2022	Buy	20,000	7.90 USD	$158K	conv 25Cluster	SEC

Company	Filed	Type	Qty	Price	Value · USD	Signals	Src
Werewolf Therapeutics, Inc.Listing on record	May 14, 2025	Buy	162,539	0.98 USD	$159.3K	conv 30	SEC
Werewolf Therapeutics, Inc.Listing on record	May 14, 2025	Buy	320,913	0.86 USD	$276K	conv 42First in 12mo	SEC
Werewolf Therapeutics, Inc.Listing on record	May 14, 2025	Buy	52,974	0.98 USD	$51.9K	conv 29	SEC
PepGen Inc.Listing on record	Jun 21, 2024	AwardD (derivative)	13,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	Award	164,729	—	n/a (No price was disclosed in the filing)		SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	AwardD (derivative)	10,580	—	n/a (No price was disclosed in the filing)		SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	Award	694,755	—	n/a (No price was disclosed in the filing)		SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	Buy	933,038	15.03 USD	$14M	conv 44	SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	AwardD (derivative)	54,582	—	n/a (No price was disclosed in the filing)		SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	AwardD (derivative)	27,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	Buy	64,971	15.03 USD	$976.5K	conv 30	SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	AwardD (derivative)	5,371	—	n/a (No price was disclosed in the filing)		SEC
LENZ Therapeutics, Inc.Listing on record	Mar 25, 2024	Award	2,386,301	—	n/a (No price was disclosed in the filing)		SEC
AN2 Therapeutics, Inc.Listing on record	Aug 22, 2023	Buy	1,777,778	9.00 USD	$16M	conv 41	SEC
Janux Therapeutics, Inc.Listing on record	Jul 21, 2023	Buy	495,008	12.46 USD	$6.2M	conv 35	SEC
Janux Therapeutics, Inc.Listing on record	Jul 21, 2023	BuyD (derivative)	503,226	12.46 USD	$6.3M		SEC
Janux Therapeutics, Inc.Listing on record	Jun 16, 2023	AwardD (derivative)	12,500	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Acumen Pharmaceuticals, Inc.Listing on record	Jun 13, 2023	AwardD (derivative)	-25,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
DICE Therapeutics, Inc.Listing unverified	Mar 30, 2023	Buy	195,997	28.74 USD	$5.6M	conv 21	SEC
DICE Therapeutics, Inc.Listing unverified	Mar 30, 2023	Buy	66,369	29.38 USD	$1.9M	conv 20	SEC
DICE Therapeutics, Inc.Listing unverified	Mar 30, 2023	Buy	246,779	29.24 USD	$7.2M	conv 29	SEC
AN2 Therapeutics, Inc.Listing on record	Jul 28, 2022	Buy	14,938	7.71 USD	$115.2K	conv 21	SEC
AN2 Therapeutics, Inc.Listing on record	Jul 28, 2022	Buy	8,281	7.91 USD	$65.5K	conv 19	SEC
AN2 Therapeutics, Inc.Listing on record	Jun 15, 2022	Buy	61,424	7.97 USD	$489.5K	conv 25Cluster	SEC
AN2 Therapeutics, Inc.Listing on record	Jun 15, 2022	Buy	20,000	7.90 USD	$158K	conv 25Cluster	SEC