RA Capital Nexus Fund III, L.P.

10% owner at Bicara Therapeutics Inc. · on record since Sep 12, 2024
Director at Septerna, Inc. · on record since Oct 30, 2024
Director at Sionna Therapeutics, Inc. · on record since Feb 10, 2025
Director at Evommune, Inc. · on record since Nov 5, 2025
Director at Merck & Co., Inc. · on record since Feb 11, 2026
Director at Freenome, Inc. · on record since Jul 22, 2026
Director at Climb Bio, Inc. · on record since Apr 29, 2026
10% owner at Climb Bio, Inc. · on record since Apr 29, 2026
Director at Artiva Biotherapeutics, Inc. · on record since May 13, 2026
Director at Parabilis Medicines, Inc. · on record since Jun 9, 2026
Director at Bicara Therapeutics Inc. · on record since Jun 10, 2026
Director at Mineralys Therapeutics, Inc. · on record since Feb 16, 2023
10% owner at Mineralys Therapeutics, Inc. · on record since Feb 13, 2023

Insider trading activity of RA Capital Nexus Fund III, L.P.

Transactions on record: 24; since Feb 16, 2023

Open-market buys: 5; $70.5M

Open-market sells: 8; $14.8M

Companies traded: 3; last filing Oct 28, 2025

Figures computed from official regulatory filings — .

Companies where RA Capital Nexus Fund III, L.P. has traded

Sionna Therapeutics, Inc.8 tx · $14.8M · Oct 28, 2025
Bicara Therapeutics Inc.9 tx · $33M · Jun 10, 2025
Mineralys Therapeutics, Inc.7 tx · $37.5M · Mar 17, 2025

Track record of RA Capital Nexus Fund III, L.P.

Statistical track record

Free account

Open-market buys: 5

Last buy: Mar 13, 2025

Win rates, median returns and the proven-insider analysis come with a free account.

Transaction history of RA Capital Nexus Fund III, L.P.

Co-insiders of RA Capital Nexus Fund III, L.P.

This page republishes public regulatory disclosures.

Company	Filed	Type	Qty	Price	Value · USD	Signals	Src
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-66,672	39.50 USD	$2.6M		SEC
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-10,476	39.58 USD	$414.6K		SEC
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-14,116	39.50 USD	$557.6K		SEC
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-107,941	39.50 USD	$4.3M		SEC
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-17,118	39.58 USD	$677.5K		SEC
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-3,624	39.58 USD	$143.4K		SEC
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-31,392	39.58 USD	$1.2M		SEC
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-122,271	39.50 USD	$4.8M		SEC
Bicara Therapeutics Inc.Listing unverified	Jun 10, 2025	AwardD (derivative)	23,746	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Mineralys Therapeutics, Inc.Listing on record	Mar 17, 2025	Buy	1,296,296	13.50 USD	$17.5M	conv 47Cluster	SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	OtherD (derivative)	-18,409,755	—	n/a (No price was disclosed in the filing)		SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	Other	2,500,095	—	n/a (No price was disclosed in the filing)		SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	OtherD (derivative)	-10,836,474	—	n/a (No price was disclosed in the filing)		SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	OtherD (derivative)	-12,273,169	—	n/a (No price was disclosed in the filing)		SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	Buy	152,480	18.00 USD	$2.7M	conv 53First in 12mo	SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	Other	2,622,898	—	n/a (No price was disclosed in the filing)		SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	Buy	1,680,520	18.00 USD	$30.2M	conv 76First in 12mo	SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	OtherD (derivative)	-5,835,024	—	n/a (No price was disclosed in the filing)		SEC
Mineralys Therapeutics, Inc.Listing on record	Feb 16, 2023	Other	1,735,629	—	n/a (No price was disclosed in the filing)		SEC
Mineralys Therapeutics, Inc.Listing on record	Feb 16, 2023	Buy	1,118,400	16.00 USD	$17.9M	conv 74ClusterFirst in 12mo	SEC
Mineralys Therapeutics, Inc.Listing on record	Feb 16, 2023	OtherD (derivative)	-192,847	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Mineralys Therapeutics, Inc.Listing on record	Feb 16, 2023	OtherD (derivative)	-1,735,629	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Mineralys Therapeutics, Inc.Listing on record	Feb 16, 2023	Other	192,847	—	n/a (No price was disclosed in the filing)		SEC
Mineralys Therapeutics, Inc.Listing on record	Feb 16, 2023	Buy	131,600	16.00 USD	$2.1M	conv 44ClusterFirst in 12mo	SEC

Company	Filed	Type	Qty	Price	Value · USD	Signals	Src
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-66,672	39.50 USD	$2.6M		SEC
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-10,476	39.58 USD	$414.6K		SEC
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-14,116	39.50 USD	$557.6K		SEC
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-107,941	39.50 USD	$4.3M		SEC
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-17,118	39.58 USD	$677.5K		SEC
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-3,624	39.58 USD	$143.4K		SEC
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-31,392	39.58 USD	$1.2M		SEC
Sionna Therapeutics, Inc.Listing unverified	Oct 28, 2025	Sell	-122,271	39.50 USD	$4.8M		SEC
Bicara Therapeutics Inc.Listing unverified	Jun 10, 2025	AwardD (derivative)	23,746	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Mineralys Therapeutics, Inc.Listing on record	Mar 17, 2025	Buy	1,296,296	13.50 USD	$17.5M	conv 47Cluster	SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	OtherD (derivative)	-18,409,755	—	n/a (No price was disclosed in the filing)		SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	Other	2,500,095	—	n/a (No price was disclosed in the filing)		SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	OtherD (derivative)	-10,836,474	—	n/a (No price was disclosed in the filing)		SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	OtherD (derivative)	-12,273,169	—	n/a (No price was disclosed in the filing)		SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	Buy	152,480	18.00 USD	$2.7M	conv 53First in 12mo	SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	Other	2,622,898	—	n/a (No price was disclosed in the filing)		SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	Buy	1,680,520	18.00 USD	$30.2M	conv 76First in 12mo	SEC
Bicara Therapeutics Inc.Listing unverified	Sep 18, 2024	OtherD (derivative)	-5,835,024	—	n/a (No price was disclosed in the filing)		SEC
Mineralys Therapeutics, Inc.Listing on record	Feb 16, 2023	Other	1,735,629	—	n/a (No price was disclosed in the filing)		SEC
Mineralys Therapeutics, Inc.Listing on record	Feb 16, 2023	Buy	1,118,400	16.00 USD	$17.9M	conv 74ClusterFirst in 12mo	SEC
Mineralys Therapeutics, Inc.Listing on record	Feb 16, 2023	OtherD (derivative)	-192,847	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Mineralys Therapeutics, Inc.Listing on record	Feb 16, 2023	OtherD (derivative)	-1,735,629	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Mineralys Therapeutics, Inc.Listing on record	Feb 16, 2023	Other	192,847	—	n/a (No price was disclosed in the filing)		SEC
Mineralys Therapeutics, Inc.Listing on record	Feb 16, 2023	Buy	131,600	16.00 USD	$2.1M	conv 44ClusterFirst in 12mo	SEC