Baker Brothers Life Sciences LP

Director at MADRIGAL PHARMACEUTICALS, INC. · on record since Jun 20, 2023
Former 10% Owner at Neurogene Inc. · on record since Dec 20, 2023
Former 10% Owner at Seagen Inc. · on record since Dec 18, 2023
Director at vTv Therapeutics Inc. · on record since Mar 7, 2024
Director at Immunocore Holdings plc · on record since May 29, 2024
Director at BICYCLE THERAPEUTICS PLC · on record since May 29, 2024
10% owner at BICYCLE THERAPEUTICS PLC · on record since May 29, 2024
Director at Kymera Therapeutics, Inc. · on record since Apr 1, 2024
Director at TScan Therapeutics, Inc. · on record since May 22, 2026
Former 10% owner and director at IGM Biosciences, Inc. · on record since Aug 18, 2025
10% owner at Kymera Therapeutics, Inc. · on record since Dec 11, 2025
Director at INCYTE CORP · on record since Apr 2, 2026
10% owner at INCYTE CORP · on record since Apr 2, 2026
Director at Replimune Group, Inc. · on record since Apr 7, 2026
10% owner at Replimune Group, Inc. · on record since Apr 7, 2026
Director at BeOne Medicines Ltd. · on record since May 27, 2026
Director at Prelude Therapeutics Inc · on record since Apr 22, 2026
10% owner at Prelude Therapeutics Inc · on record since Apr 22, 2026
Director at · on record since Jul 31, 2012
Director at · on record since Jul 23, 2012
Director at · on record since Jul 13, 2012
10% owner at · on record since Jul 13, 2012
10% owner at · on record since Oct 31, 2012
10% owner at · on record since Nov 23, 2012
Director at · on record since Jan 23, 2013
10% owner at · on record since Jan 23, 2013
Director at · on record since May 21, 2013
10% owner at · on record since May 21, 2013
10% owner at · on record since Aug 2, 2013
Director at · on record since Mar 19, 2014
Director at · on record since Jun 2, 2026
Director at · on record since Jun 5, 2026
10% owner at · on record since Feb 2, 2015
Director at · on record since Jun 30, 2015
Former 10% owner and Director at · on record since Jun 23, 2015
Former 10% owner at · on record since Jul 23, 2015
10% owner at · on record since Aug 10, 2015
10% owner at · on record since Feb 9, 2016
Director at · on record since May 9, 2017
10% owner at · on record since Mar 15, 2018
10% owner at · on record since May 31, 2018
Director at · on record since Oct 11, 2018
10% owner at · on record since Oct 11, 2018
Director at · on record since Sep 20, 2019
10% owner at · on record since Sep 20, 2019
Director at · on record since Dec 20, 2019
10% owner at · on record since Oct 15, 2019
Director at · on record since Mar 16, 2020
Director at · on record since Feb 25, 2021
Director at · on record since Feb 19, 2021
10% owner at · on record since Feb 19, 2021
Director at · on record since Jan 11, 2021
10% owner at · on record since Jan 11, 2021
10% owner at · on record since Jul 15, 2021

Insider trading activity of Baker Brothers Life Sciences LP

Transactions on record: 549; since Nov 14, 2012

Open-market buys: 241; $1.1B

Open-market sells: 133; $793.8M

Companies traded: 16; last filing Dec 19, 2025

Figures computed from official regulatory filings — .

Companies where Baker Brothers Life Sciences LP has traded

75 tx · $315.6M · Dec 19, 2025
85 tx · $103.5B · Jul 2, 2025
4 tx · $25M · Jun 13, 2025
14 tx · $649.1M · May 22, 2025
4 tx · Mar 31, 2025
21 tx · $3.4M · Jan 3, 2025
28 tx · $84M · Oct 8, 2024
32 tx · $11.9M · Nov 21, 2023
14 tx · $1.5M · Aug 17, 2023
1 tx · Jun 13, 2022
64 tx · $473.1M · Dec 2, 2021
9 tx · $77.5M · Sep 20, 2019
147 tx · $81.8M · Mar 14, 2019
14 tx · $32.2M · Jul 5, 2018

Track record of Baker Brothers Life Sciences LP

Statistical track record

Free account

Open-market buys: 261

Last buy: Dec 18, 2025

Win rates, median returns and the proven-insider analysis come with a free account.

Transaction history of Baker Brothers Life Sciences LP

Co-insiders of Baker Brothers Life Sciences LP

This page republishes public regulatory disclosures.

Company	Filed	Type	Qty	Price	Value · USD	Signals	Src
Kodiak Sciences Inc.Listing on record	Dec 19, 2025	Buy	2,391,268	23.00 USD	$55M	conv 57Unusual sizeFirst in 12mo	SEC
Kodiak Sciences Inc.Listing on record	Dec 19, 2025	Buy	217,428	23.00 USD	$5M	conv 57Unusual sizeFirst in 12mo	SEC
INCYTE CORPListing on record	Jul 2, 2025	Award	492	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
INCYTE CORPListing on record	Jul 2, 2025	Award	492	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Prelude Therapeutics IncListing on record	Jun 13, 2025	AwardD (derivative)	76,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Prelude Therapeutics IncListing on record	Jun 13, 2025	AwardD (derivative)	76,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
INCYTE CORPListing on record	Jun 12, 2025	AwardD (derivative)	9,216	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
INCYTE CORPListing on record	Jun 12, 2025	Award	2,518	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
INCYTE CORPListing on record	Jun 12, 2025	AwardD (derivative)	9,216	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
INCYTE CORPListing on record	Jun 12, 2025	Award	2,518	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
BeOne Medicines Ltd.Listing on record	May 22, 2025	AwardD (derivative)	45,500	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
BeOne Medicines Ltd.Listing on record	May 22, 2025	Award	21,970	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
BeOne Medicines Ltd.Listing on record	May 22, 2025	Award	21,970	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
BeOne Medicines Ltd.Listing on record	May 22, 2025	AwardD (derivative)	45,500	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
DBV Technologies S.A.Listing on record	Mar 31, 2025	AwardD (derivative)	2,299,656	—	n/a (No price was disclosed in the filing)		SEC
DBV Technologies S.A.Listing on record	Mar 31, 2025	AwardD (derivative)	2,299,656	—	n/a (No price was disclosed in the filing)		SEC
DBV Technologies S.A.Listing on record	Mar 31, 2025	AwardD (derivative)	25,005,240	—	n/a (No price was disclosed in the filing)		SEC
DBV Technologies S.A.Listing on record	Mar 31, 2025	AwardD (derivative)	25,005,240	—	n/a (No price was disclosed in the filing)		SEC
IGM Biosciences, Inc.Listing unverified	Jan 3, 2025	Award	1,994	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
IGM Biosciences, Inc.Listing unverified	Jan 3, 2025	Award	1,994	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
BeOne Medicines Ltd.Listing on record	Dec 10, 2024	Sell	-83,036	186.50 USD	$15.5M		SEC
BeOne Medicines Ltd.Listing on record	Dec 10, 2024	Sell	-3,074	208.01 USD	$639.4K		SEC
BeOne Medicines Ltd.Listing on record	Dec 10, 2024	Sell	-916,964	186.50 USD	$171M	Unusual size	SEC
BeOne Medicines Ltd.Listing on record	Dec 10, 2024	Sell	-33,943	208.01 USD	$7.1M		SEC
Kiniksa Pharmaceuticals International, plcListing on record	Oct 8, 2024	AwardD (derivative)	28,384	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC

Company	Filed	Type	Qty	Price	Value · USD	Signals	Src
Kodiak Sciences Inc.Listing on record	Dec 19, 2025	Buy	2,391,268	23.00 USD	$55M	conv 57Unusual sizeFirst in 12mo	SEC
Kodiak Sciences Inc.Listing on record	Dec 19, 2025	Buy	217,428	23.00 USD	$5M	conv 57Unusual sizeFirst in 12mo	SEC
INCYTE CORPListing on record	Jul 2, 2025	Award	492	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
INCYTE CORPListing on record	Jul 2, 2025	Award	492	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Prelude Therapeutics IncListing on record	Jun 13, 2025	AwardD (derivative)	76,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Prelude Therapeutics IncListing on record	Jun 13, 2025	AwardD (derivative)	76,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
INCYTE CORPListing on record	Jun 12, 2025	AwardD (derivative)	9,216	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
INCYTE CORPListing on record	Jun 12, 2025	Award	2,518	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
INCYTE CORPListing on record	Jun 12, 2025	AwardD (derivative)	9,216	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
INCYTE CORPListing on record	Jun 12, 2025	Award	2,518	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
BeOne Medicines Ltd.Listing on record	May 22, 2025	AwardD (derivative)	45,500	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
BeOne Medicines Ltd.Listing on record	May 22, 2025	Award	21,970	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
BeOne Medicines Ltd.Listing on record	May 22, 2025	Award	21,970	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
BeOne Medicines Ltd.Listing on record	May 22, 2025	AwardD (derivative)	45,500	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
DBV Technologies S.A.Listing on record	Mar 31, 2025	AwardD (derivative)	2,299,656	—	n/a (No price was disclosed in the filing)		SEC
DBV Technologies S.A.Listing on record	Mar 31, 2025	AwardD (derivative)	2,299,656	—	n/a (No price was disclosed in the filing)		SEC
DBV Technologies S.A.Listing on record	Mar 31, 2025	AwardD (derivative)	25,005,240	—	n/a (No price was disclosed in the filing)		SEC
DBV Technologies S.A.Listing on record	Mar 31, 2025	AwardD (derivative)	25,005,240	—	n/a (No price was disclosed in the filing)		SEC
IGM Biosciences, Inc.Listing unverified	Jan 3, 2025	Award	1,994	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
IGM Biosciences, Inc.Listing unverified	Jan 3, 2025	Award	1,994	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
BeOne Medicines Ltd.Listing on record	Dec 10, 2024	Sell	-83,036	186.50 USD	$15.5M		SEC
BeOne Medicines Ltd.Listing on record	Dec 10, 2024	Sell	-3,074	208.01 USD	$639.4K		SEC
BeOne Medicines Ltd.Listing on record	Dec 10, 2024	Sell	-916,964	186.50 USD	$171M	Unusual size	SEC
BeOne Medicines Ltd.Listing on record	Dec 10, 2024	Sell	-33,943	208.01 USD	$7.1M		SEC
Kiniksa Pharmaceuticals International, plcListing on record	Oct 8, 2024	AwardD (derivative)	28,384	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC