Baker Bros. Advisors (GP) LLC

Director at SYNTA PHARMACEUTICALS CORP · on record since Jun 20, 2023
Former 10% Owner at Atreca, Inc. · on record since Oct 23, 2023
Former 10% Owner at Neurogene Inc. · on record since Dec 20, 2023
Former 10% Owner at SEATTLE GENETICS INC /WA · on record since Dec 18, 2023
10% owner at Mirati Therapeutics, Inc. · on record since Oct 28, 2013
Director at vTv Therapeutics Inc. · on record since Mar 7, 2024
Director at Immunocore Holdings plc · on record since May 29, 2024
Director at BICYCLE THERAPEUTICS PLC · on record since May 29, 2024
10% owner at BICYCLE THERAPEUTICS PLC · on record since May 29, 2024
10% owner at Kala Pharmaceuticals, Inc. · on record since Jun 28, 2024
Director at Kymera Therapeutics, Inc. · on record since Apr 1, 2024
Director at TScan Therapeutics, Inc. · on record since May 22, 2026
10% owner at SERA PROGNOSTICS, INC. · on record since Feb 14, 2025
Former 10% owner and director at IGM Biosciences, Inc. · on record since Aug 18, 2025
10% owner at Celcuity Inc. · on record since Sep 10, 2025
10% owner at Kymera Therapeutics, Inc. · on record since Dec 11, 2025
Former 10% owner at Kala Pharmaceuticals, Inc. · on record since Oct 2, 2025
Director at INCYTE CORP · on record since Apr 2, 2026
10% owner at INCYTE CORP · on record since Apr 2, 2026
Director at Replimune Group, Inc. · on record since Apr 7, 2026
10% owner at Replimune Group, Inc. · on record since Apr 7, 2026
Director at BeOne Medicines Ltd. · on record since May 27, 2026
Director at Prelude Therapeutics Inc · on record since Apr 22, 2026
10% owner at Prelude Therapeutics Inc · on record since Apr 22, 2026
Director at GENOMIC HEALTH INC · on record since Jul 29, 2013
10% owner at GENOMIC HEALTH INC · on record since Jul 29, 2013
Director at XOMA LTD /DE/ · on record since Aug 21, 2013
10% owner at XOMA LTD /DE/ · on record since Aug 21, 2013
10% owner at BIOCRYST PHARMACEUTICALS INC · on record since Jul 11, 2013
Director at ACADIA PHARMACEUTICALS INC · on record since Jul 11, 2013
10% owner at ACADIA PHARMACEUTICALS INC · on record since Jul 11, 2013
Director at SEATTLE GENETICS INC /WA · on record since Jul 11, 2013
10% owner at SEATTLE GENETICS INC /WA · on record since Jul 11, 2013
10% owner at MAYTAG CORP · on record since Jul 11, 2013
Director at TRIMERIS INC · on record since Jul 11, 2013
10% owner at TRIMERIS INC · on record since Jul 11, 2013
Director at IDERA PHARMACEUTICALS, INC. · on record since Mar 19, 2014
Director at Kiniksa Pharmaceuticals International, plc · on record since Jun 2, 2026
Director at Denali Therapeutics Inc. · on record since Jun 5, 2026
Director at ALEXION PHARMACEUTICALS INC · on record since Jun 30, 2015
Former 10% owner and Director at TRIMERIS INC · on record since Jun 23, 2015
10% owner at Invitae Corp · on record since Aug 27, 2015
Former 10% owner at XOMA LTD /DE/ · on record since Jul 23, 2015
10% owner at Neurogene Inc. · on record since Sep 11, 2015
10% owner at BELLICUM PHARMACEUTICALS, INC · on record since Dec 24, 2015
10% owner at BeOne Medicines Ltd. · on record since Feb 9, 2016
Former 10% owner at Intellia Therapeutics, Inc. · on record since May 11, 2016
10% owner at Intellia Therapeutics, Inc. · on record since May 5, 2016
Director at Neurogene Inc. · on record since May 9, 2017
Former 10% Owner at Mirati Therapeutics, Inc. · on record since Nov 20, 2017
Former 10% owner at RHYTHM PHARMACEUTICALS, INC. · on record since Oct 6, 2017
10% owner at RHYTHM PHARMACEUTICALS, INC. · on record since Oct 4, 2017
10% owner at IDERA PHARMACEUTICALS, INC. · on record since Mar 15, 2018
10% owner at Kiniksa Pharmaceuticals International, plc · on record since May 31, 2018
10% owner at Principia Biopharma Inc. · on record since Sep 13, 2018
Director at Kodiak Sciences Inc. · on record since Oct 11, 2018
10% owner at Kodiak Sciences Inc. · on record since Oct 11, 2018
10% owner at Atreca, Inc. · on record since Jun 26, 2019
Former 10% owner at REDHOOK ALE BREWERY INC · on record since Apr 23, 2019
10% owner at REDHOOK ALE BREWERY INC · on record since Apr 18, 2019
Director at IGM Biosciences, Inc. · on record since Sep 20, 2019
10% owner at IGM Biosciences, Inc. · on record since Sep 20, 2019
Director at SMI PRODUCTS INC · on record since Dec 20, 2019
10% owner at SMI PRODUCTS INC · on record since Oct 15, 2019
Director at Zymeworks Inc. · on record since Mar 16, 2020
Director at Spyre Therapeutics, Inc. · on record since Feb 25, 2021
Director at Talis Biomedical Corp · on record since Feb 19, 2021
10% owner at Talis Biomedical Corp · on record since Feb 19, 2021
Director at DBV Technologies S.A. · on record since Jan 11, 2021
10% owner at DBV Technologies S.A. · on record since Jan 11, 2021
10% owner at TScan Therapeutics, Inc. · on record since Jul 15, 2021
10% owner at Entrada Therapeutics, Inc. · on record since Dec 16, 2021

Insider trading activity of Baker Bros. Advisors (GP) LLC

Transactions on record: 405; since May 29, 2014

Open-market buys: 181; $413.7M

Open-market sells: 62; $247.6M

Companies traded: 27; last filing Nov 12, 2025

Figures computed from official regulatory filings — methodology.

Companies where Baker Bros. Advisors (GP) LLC has traded

Entrada Therapeutics, Inc.18 tx · $1.6M · Nov 12, 2025
Celcuity Inc.4 tx · $9.6M · Sep 10, 2025
SYNTA PHARMACEUTICALS CORP30 tx · $36.9M · Aug 20, 2025
Kymera Therapeutics, Inc.4 tx · $57.7M · Jun 30, 2025
ACADIA PHARMACEUTICALS INC8 tx · $3.9M · Jun 2, 2025
Immunocore Holdings plc4 tx · May 19, 2025
Replimune Group, Inc.2 tx · Mar 7, 2025
BeOne Medicines Ltd.9 tx · $190.5M · Feb 28, 2025
BICYCLE THERAPEUTICS PLC10 tx · $21.2M · Dec 17, 2024

Track record of Baker Bros. Advisors (GP) LLC

Statistical track record

Free

Open-market buys: 187

Last buy: Nov 12, 2025

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Transaction history of Baker Bros. Advisors (GP) LLC

Co-insiders of Baker Bros. Advisors (GP) LLC

This page republishes public regulatory disclosures. Concerned by this data? Exercise your right to object →

Company	Filed	Type	Qty	Price	Value · USD	Src
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	1,040	7.95 USD	$8.3K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	25,364	7.21 USD	$182.9K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	2,947	7.22 USD	$21.3K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	80,881	7.73 USD	$625.2K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	30,879	7.54 USD	$232.8K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	11,494	7.95 USD	$91.4K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	267	7.22 USD	$1.9K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	7,321	7.73 USD	$56.6K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	11,701	7.39 USD	$86.5K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	1,059	7.39 USD	$7.8K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	2,795	7.54 USD	$21.1K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	2,296	7.21 USD	$16.6K	SEC
Celcuity Inc.	Sep 10, 2025	Buy	4,212	58.02 USD	$244.4K	SEC
Celcuity Inc.	Sep 10, 2025	Buy	13,976	56.22 USD	$785.7K	SEC
Celcuity Inc.	Sep 10, 2025	Buy	388	58.02 USD	$22.5K	SEC
Celcuity Inc.	Sep 10, 2025	Buy	151,524	56.22 USD	$8.5M	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	4,441	387.07 USD	$1.7M	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	5,209	380.44 USD	$2M	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	231	389.89 USD	$90.1K	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	105	382.29 USD	$40.1K	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	2,838	382.82 USD	$1.1M	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	873	381.12 USD	$332.7K	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	2,460	372.87 USD	$917.3K	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	2,506	389.89 USD	$977.1K	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	9,477	381.12 USD	$3.6M	SEC

Company	Filed	Type	Qty	Price	Value · USD	Src
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	1,040	7.95 USD	$8.3K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	25,364	7.21 USD	$182.9K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	2,947	7.22 USD	$21.3K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	80,881	7.73 USD	$625.2K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	30,879	7.54 USD	$232.8K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	11,494	7.95 USD	$91.4K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	267	7.22 USD	$1.9K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	7,321	7.73 USD	$56.6K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	11,701	7.39 USD	$86.5K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	1,059	7.39 USD	$7.8K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	2,795	7.54 USD	$21.1K	SEC
Entrada Therapeutics, Inc.	Nov 12, 2025	Buy	2,296	7.21 USD	$16.6K	SEC
Celcuity Inc.	Sep 10, 2025	Buy	4,212	58.02 USD	$244.4K	SEC
Celcuity Inc.	Sep 10, 2025	Buy	13,976	56.22 USD	$785.7K	SEC
Celcuity Inc.	Sep 10, 2025	Buy	388	58.02 USD	$22.5K	SEC
Celcuity Inc.	Sep 10, 2025	Buy	151,524	56.22 USD	$8.5M	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	4,441	387.07 USD	$1.7M	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	5,209	380.44 USD	$2M	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	231	389.89 USD	$90.1K	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	105	382.29 USD	$40.1K	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	2,838	382.82 USD	$1.1M	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	873	381.12 USD	$332.7K	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	2,460	372.87 USD	$917.3K	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	2,506	389.89 USD	$977.1K	SEC
SYNTA PHARMACEUTICALS CORP	Aug 20, 2025	Buy	9,477	381.12 USD	$3.6M	SEC