BAKER BROS. ADVISORS LP

Director at SYNTA PHARMACEUTICALS CORP · on record since Jun 20, 2023
Former 10% Owner at Atreca, Inc. · on record since Oct 23, 2023
Former 10% Owner at Neurogene Inc. · on record since Dec 20, 2023
Former 10% Owner at SEATTLE GENETICS INC /WA · on record since Dec 18, 2023
10% owner at Mirati Therapeutics, Inc. · on record since Oct 28, 2013
Director at vTv Therapeutics Inc. · on record since Mar 7, 2024
Director at Immunocore Holdings plc · on record since May 29, 2024
Director at BICYCLE THERAPEUTICS PLC · on record since May 29, 2024
10% owner at BICYCLE THERAPEUTICS PLC · on record since May 29, 2024
10% owner at Kala Pharmaceuticals, Inc. · on record since Jun 28, 2024
Director at Kymera Therapeutics, Inc. · on record since Apr 1, 2024
Director at TScan Therapeutics, Inc. · on record since May 22, 2026
10% owner at SERA PROGNOSTICS, INC. · on record since Feb 14, 2025
Former 10% owner and director at IGM Biosciences, Inc. · on record since Aug 18, 2025
10% owner at Celcuity Inc. · on record since Sep 10, 2025
10% owner at Kymera Therapeutics, Inc. · on record since Dec 11, 2025
Former 10% owner at Kala Pharmaceuticals, Inc. · on record since Oct 2, 2025
Director at INCYTE CORP · on record since Apr 2, 2026
10% owner at · on record since Apr 2, 2026
Director at · on record since Apr 7, 2026
10% owner at · on record since Apr 7, 2026
Director at · on record since May 27, 2026
Director at · on record since Apr 22, 2026
10% owner at · on record since Apr 22, 2026
Director at · on record since Apr 24, 2012
10% owner at · on record since Apr 24, 2012
Director at · on record since May 23, 2012
10% owner at · on record since May 23, 2012
10% owner at · on record since Apr 23, 2012
10% owner at · on record since Apr 23, 2012
Director at · on record since Apr 23, 2012
10% owner at · on record since Apr 23, 2012
Director at · on record since Apr 23, 2012
10% owner at · on record since Apr 23, 2012
Director at · on record since Oct 31, 2012
10% owner at · on record since Dec 21, 2012
Director at · on record since Jan 23, 2013
10% owner at · on record since Jul 11, 2013
Director at · on record since Mar 19, 2014
Director at · on record since Jun 2, 2026
Director at · on record since Jun 5, 2026
Director at · on record since Jun 30, 2015
Former 10% owner and Director at · on record since Jun 23, 2015
10% owner at · on record since Aug 27, 2015
Former 10% owner at · on record since Jul 23, 2015
10% owner at · on record since Sep 11, 2015
10% owner at · on record since Dec 24, 2015
10% owner at · on record since Feb 9, 2016
Former 10% owner at · on record since May 11, 2016
10% owner at · on record since May 5, 2016
Director at · on record since May 9, 2017
Former 10% Owner at · on record since Nov 20, 2017
Former 10% owner at · on record since Oct 6, 2017
10% owner at · on record since Oct 4, 2017
10% owner at · on record since Mar 15, 2018
10% owner at · on record since May 31, 2018
10% owner at · on record since Sep 13, 2018
Director at · on record since Oct 11, 2018
10% owner at · on record since Oct 11, 2018
10% owner at · on record since Jun 26, 2019
Former 10% owner at · on record since Apr 23, 2019
10% owner at · on record since Apr 18, 2019
Director at · on record since Sep 20, 2019
10% owner at · on record since Sep 20, 2019
Director at · on record since Dec 20, 2019
10% owner at · on record since Oct 15, 2019
Director at · on record since Mar 16, 2020
Director at · on record since Feb 25, 2021
Director at · on record since Feb 19, 2021
10% owner at · on record since Feb 19, 2021
Director at · on record since Jan 11, 2021
10% owner at · on record since Jan 11, 2021
10% owner at · on record since Jul 15, 2021
10% owner at · on record since Dec 16, 2021
Former 10% owner at · on record since Jul 16, 2026

Insider trading activity of BAKER BROS. ADVISORS LP

Transactions on record: 560; since May 8, 2012

Open-market buys: 282; $1.1B

Open-market sells: 81; $358.8M

Companies traded: 29; last filing Aug 11, 2026

Figures computed from official regulatory filings — .

Companies where BAKER BROS. ADVISORS LP has traded

4 tx · $33M · Aug 11, 2026
2 tx · $317.8M · Jul 16, 2026
30 tx · $16M · Jul 2, 2026
37 tx · $36.2M · Jul 2, 2026
2 tx · Jun 29, 2026
6 tx · Jun 25, 2026
30 tx · $297.5M · Jun 18, 2026
21 tx · $640.7M · Jun 15, 2026
8 tx · $10.1M · Jun 10, 2026
8 tx · Jun 5, 2026
42 tx · $33.6M · Jun 2, 2026
6 tx · $29.2M · Jun 2, 2026
6 tx · May 22, 2026
15 tx · $3.4M · Aug 18, 2025

Track record of BAKER BROS. ADVISORS LP

Statistical track record

Free

Open-market buys: 296

Last buy: Aug 11, 2026

Win rates and median returns are available with a free account (5 insiders/month).

Transaction history of BAKER BROS. ADVISORS LP

Co-insiders of BAKER BROS. ADVISORS LP

This page republishes public regulatory disclosures.

Company	Filed	Type	Qty	Price	Value · USD	Src
Replimune Group, Inc.	Aug 11, 2026	BuyD (derivative)	126,394	12.06 USD	$1.5M	SEC
Replimune Group, Inc.	Aug 11, 2026	BuyD (derivative)	2,609,946	12.06 USD	$31.5M	SEC
Celcuity Inc.	Jul 16, 2026	Sell	-261,368	102.50 USD	$26.8M	SEC
Celcuity Inc.	Jul 16, 2026	Sell	-2,838,632	102.50 USD	$291M	SEC
INCYTE CORP	Jul 2, 2026	Award	400	0.00 USD	—	SEC
Kodiak Sciences Inc.	Jul 2, 2026	AwardD (derivative)	17,731	0.00 USD	—	SEC
INCYTE CORP	Jul 2, 2026	Award	400	0.00 USD	—	SEC
Kodiak Sciences Inc.	Jul 2, 2026	AwardD (derivative)	17,731	0.00 USD	—	SEC
vTv Therapeutics Inc.	Jun 29, 2026	AwardD (derivative)	6,000	0.00 USD	—	SEC
vTv Therapeutics Inc.	Jun 29, 2026	AwardD (derivative)	6,000	0.00 USD	—	SEC
Kymera Therapeutics, Inc.	Jun 25, 2026	AwardD (derivative)	6,068	0.00 USD	—	SEC
Kymera Therapeutics, Inc.	Jun 25, 2026	AwardD (derivative)	6,068	0.00 USD	—	SEC
SYNTA PHARMACEUTICALS CORP	Jun 18, 2026	Award	908	0.00 USD	—	SEC
SYNTA PHARMACEUTICALS CORP	Jun 18, 2026	AwardD (derivative)	1,532	0.00 USD	—	SEC
SYNTA PHARMACEUTICALS CORP	Jun 18, 2026	Award	908	0.00 USD	—	SEC
SYNTA PHARMACEUTICALS CORP	Jun 18, 2026	AwardD (derivative)	1,532	0.00 USD	—	SEC
BeOne Medicines Ltd.	Jun 15, 2026	Award	18,980	0.00 USD	—	SEC
BeOne Medicines Ltd.	Jun 15, 2026	Award	18,980	0.00 USD	—	SEC
Prelude Therapeutics Inc	Jun 10, 2026	AwardD (derivative)	38,000	0.00 USD	—	SEC
INCYTE CORP	Jun 10, 2026	Award	1,642	0.00 USD	—	SEC
INCYTE CORP	Jun 10, 2026	AwardD (derivative)	6,111	0.00 USD	—	SEC
Prelude Therapeutics Inc	Jun 10, 2026	AwardD (derivative)	38,000	0.00 USD	—	SEC
INCYTE CORP	Jun 10, 2026	AwardD (derivative)	6,111	0.00 USD	—	SEC
INCYTE CORP	Jun 10, 2026	Award	1,642	0.00 USD	—	SEC
Denali Therapeutics Inc.	Jun 5, 2026	AwardD (derivative)	19,226	0.00 USD	—	SEC

Company	Filed	Type	Qty	Price	Value · USD	Src
Replimune Group, Inc.	Aug 11, 2026	BuyD (derivative)	126,394	12.06 USD	$1.5M	SEC
Replimune Group, Inc.	Aug 11, 2026	BuyD (derivative)	2,609,946	12.06 USD	$31.5M	SEC
Celcuity Inc.	Jul 16, 2026	Sell	-261,368	102.50 USD	$26.8M	SEC
Celcuity Inc.	Jul 16, 2026	Sell	-2,838,632	102.50 USD	$291M	SEC
INCYTE CORP	Jul 2, 2026	Award	400	0.00 USD	—	SEC
Kodiak Sciences Inc.	Jul 2, 2026	AwardD (derivative)	17,731	0.00 USD	—	SEC
INCYTE CORP	Jul 2, 2026	Award	400	0.00 USD	—	SEC
Kodiak Sciences Inc.	Jul 2, 2026	AwardD (derivative)	17,731	0.00 USD	—	SEC
vTv Therapeutics Inc.	Jun 29, 2026	AwardD (derivative)	6,000	0.00 USD	—	SEC
vTv Therapeutics Inc.	Jun 29, 2026	AwardD (derivative)	6,000	0.00 USD	—	SEC
Kymera Therapeutics, Inc.	Jun 25, 2026	AwardD (derivative)	6,068	0.00 USD	—	SEC
Kymera Therapeutics, Inc.	Jun 25, 2026	AwardD (derivative)	6,068	0.00 USD	—	SEC
SYNTA PHARMACEUTICALS CORP	Jun 18, 2026	Award	908	0.00 USD	—	SEC
SYNTA PHARMACEUTICALS CORP	Jun 18, 2026	AwardD (derivative)	1,532	0.00 USD	—	SEC
SYNTA PHARMACEUTICALS CORP	Jun 18, 2026	Award	908	0.00 USD	—	SEC
SYNTA PHARMACEUTICALS CORP	Jun 18, 2026	AwardD (derivative)	1,532	0.00 USD	—	SEC
BeOne Medicines Ltd.	Jun 15, 2026	Award	18,980	0.00 USD	—	SEC
BeOne Medicines Ltd.	Jun 15, 2026	Award	18,980	0.00 USD	—	SEC
Prelude Therapeutics Inc	Jun 10, 2026	AwardD (derivative)	38,000	0.00 USD	—	SEC
INCYTE CORP	Jun 10, 2026	Award	1,642	0.00 USD	—	SEC
INCYTE CORP	Jun 10, 2026	AwardD (derivative)	6,111	0.00 USD	—	SEC
Prelude Therapeutics Inc	Jun 10, 2026	AwardD (derivative)	38,000	0.00 USD	—	SEC
INCYTE CORP	Jun 10, 2026	AwardD (derivative)	6,111	0.00 USD	—	SEC
INCYTE CORP	Jun 10, 2026	Award	1,642	0.00 USD	—	SEC
Denali Therapeutics Inc.	Jun 5, 2026	AwardD (derivative)	19,226	0.00 USD	—	SEC