THREE ARCH MANAGEMENT III LLC

10% owner at THRESHOLD PHARMACEUTICALS INC · on record since Mar 7, 2006
10% owner at ACELRX PHARMACEUTICALS INC · on record since Feb 18, 2011
Director at CONCERT PHARMACEUTICALS, INC. · on record since Feb 21, 2014
10% owner at CONCERT PHARMACEUTICALS, INC. · on record since Feb 21, 2014

Insider trading activity of THREE ARCH MANAGEMENT III LLC

Transactions on record: 43; since Feb 3, 2005

Open-market buys: 4; $6.4M

Open-market sells: 6; $5.3M

Companies traded: 3; last filing Sep 14, 2015

Figures computed from official regulatory filings — methodology.

Companies where THREE ARCH MANAGEMENT III LLC has traded

CONCERT PHARMACEUTICALS, INC.6 tx · $5.3M · Sep 14, 2015
ACELRX PHARMACEUTICALS INC27 tx · $6.4M · Feb 18, 2011
THRESHOLD PHARMACEUTICALS INC10 tx · Feb 10, 2005

Track record of THREE ARCH MANAGEMENT III LLC

Insufficient history for a statistical track record (fewer than 5 open-market buys).

Transaction history of THREE ARCH MANAGEMENT III LLC

Co-insiders of THREE ARCH MANAGEMENT III LLC

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Company	Filed	Type	Qty	Price	Value · USD	Src
CONCERT PHARMACEUTICALS, INC.	Sep 14, 2015	Sell	-58,704	18.22 USD	$1.1M	SEC
CONCERT PHARMACEUTICALS, INC.	Sep 14, 2015	Sell	-1,296	18.22 USD	$23.6K	SEC
CONCERT PHARMACEUTICALS, INC.	Sep 14, 2015	Sell	-3,062	18.22 USD	$55.8K	SEC
CONCERT PHARMACEUTICALS, INC.	Sep 14, 2015	Sell	-56,938	18.22 USD	$1M	SEC
CONCERT PHARMACEUTICALS, INC.	Nov 20, 2014	Sell	-237,245	12.29 USD	$2.9M	SEC
CONCERT PHARMACEUTICALS, INC.	Nov 20, 2014	Sell	-12,755	12.29 USD	$156.8K	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-22,959	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Other	25,106	—	—	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-4,838	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-311,384	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	1,297	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-6,135	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-44,702	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Other	44,702	—	—	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Buy	65,806	5.00 USD	$329K	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-427,040	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Other	31,357	—	—	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Other	466,990	—	—	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-89,993	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Buy	1,223,983	5.00 USD	$6.1M	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-114,123	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Other	583,255	—	—	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-16,741	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Other	26,615	—	—	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Other	1,430	—	—	SEC

Company	Filed	Type	Qty	Price	Value · USD	Src
CONCERT PHARMACEUTICALS, INC.	Sep 14, 2015	Sell	-58,704	18.22 USD	$1.1M	SEC
CONCERT PHARMACEUTICALS, INC.	Sep 14, 2015	Sell	-1,296	18.22 USD	$23.6K	SEC
CONCERT PHARMACEUTICALS, INC.	Sep 14, 2015	Sell	-3,062	18.22 USD	$55.8K	SEC
CONCERT PHARMACEUTICALS, INC.	Sep 14, 2015	Sell	-56,938	18.22 USD	$1M	SEC
CONCERT PHARMACEUTICALS, INC.	Nov 20, 2014	Sell	-237,245	12.29 USD	$2.9M	SEC
CONCERT PHARMACEUTICALS, INC.	Nov 20, 2014	Sell	-12,755	12.29 USD	$156.8K	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-22,959	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Other	25,106	—	—	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-4,838	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-311,384	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	1,297	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-6,135	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-44,702	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Other	44,702	—	—	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Buy	65,806	5.00 USD	$329K	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-427,040	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Other	31,357	—	—	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Other	466,990	—	—	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-89,993	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Buy	1,223,983	5.00 USD	$6.1M	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-114,123	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Other	583,255	—	—	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	OtherD	-16,741	0.00 USD	$0	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Other	26,615	—	—	SEC
ACELRX PHARMACEUTICALS INC	Feb 18, 2011	Other	1,430	—	—	SEC