ALTA BIOPHARMA PARTNERS III GMBH & CO BETEILIGUNGS KG

• 10% owner at THRESHOLD PHARMACEUTICALS INC · on record since Sep 5, 2008
• 10% owner at AXONYX INC · on record since Oct 5, 2006
• 10% owner at COTHERIX INC · on record since Jan 9, 2007
• Nolonger 10% Owner at COTHERIX INC · on record since Jan 9, 2007
• 10% owner at NeurogesX Inc · on record since May 8, 2007
• 10% owner at SUNESIS PHARMACEUTICALS INC · on record since Apr 7, 2009
• No longer 10% owner at AXONYX INC · on record since Sep 8, 2009
• Former 10% owner at THRESHOLD PHARMACEUTICALS INC · on record since Oct 6, 2009
• Former 10% Owner at SUNESIS PHARMACEUTICALS INC · on record since Jul 2, 2010
• 10% owner at Cara Therapeutics, Inc. · on record since Jan 30, 2014
• 10% owner at Aegerion Pharmaceuticals, Inc. · on record since Oct 27, 2010
• 10% owner at MACROGENICS INC · on record since Oct 18, 2013
• 10% owner at CymaBay Therapeutics, Inc. · on record since Oct 11, 2013
• Stockholder at Comtrix, Inc. · on record since Apr 16, 2013
• 10% owner at Comtrix, Inc. · on record since Apr 10, 2013