Machine signal
Active cluster sell — 5 distinct insiders, $27.6K, window ends Sep 16, 2026.
Figures computed from official regulatory filings — .
Analysttarget 31.14 USD (+542%) · consensus 4.29/5 · 5 buy · 2 hold · 0 sell
Ownershipinsiders 14.78% · institutions 92.46% · short 12.6% of float
In USD · as of Oct 5, 2026
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Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. It offers verekitug, which is in Phase 2 trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease and in Phase I clinical trial for treating chronic obstructive pulmonary disease. The company was incorporated in 2021 and is headquartered in Waltham, Massachusetts.
Market information source · Oct 5, 2026
SEC company identity · Oct 5, 2026
Open-market timeline · full history
5 buys15 sells— close pricebar = usd volume, √ scaleclick a period to filter the table
| Insider | Type | Value · USD | Signals | Details | |
|---|---|---|---|---|---|
| Ambrose Allison | Sell | $2.7K | SEC |
| GRAY MICHAEL | Sell | $4.7K | SEC |
| Houghton Adam | Sell | $3.8K | SEC |
| Deykin Aaron | Sell | $4.9K | SEC |
| Sutherland Everett Rand | Sell | $11.5K | SEC |
| Ambrose Allison | Sell | $2.9K | SEC |
| GRAY MICHAEL | Sell | $5.2K | SEC |
| Houghton Adam | Sell | $4.3K | SEC |
| Sutherland Everett Rand | Sell | $12.8K | SEC |
| Deykin Aaron | Sell | $5.5K | SEC |
| Renaud Ronald C JR | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Ruddy Marcella K. | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Beckman Daniella | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Chimovits Ereztrack record | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Ratcliffe Liamtrack record | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Fleming Harold Edward | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Deykin Aaron | Sell | $8.3K | SEC |
| GRAY MICHAEL | Sell | $7.9K | SEC |
| Houghton Adam | Sell | $6.5K | SEC |
| Ambrose Allison | Sell | $4.4K | SEC |
| Sutherland Everett Rand | Sell | $19.4K | SEC |
| Houghton Adam | Award | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| GRAY MICHAEL | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| GRAY MICHAEL | Award | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Sutherland Everett Rand | Award | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |