Figures computed from official regulatory filings — .
Analysttarget 7.11 USD (+122%) · consensus 4.5/5 · 11 buy · 3 hold · 0 sell
Ownershipinsiders 20.3% · institutions 71% · short 22.7% of float
In USD · as of Oct 5, 2026
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Prime Medicine, Inc., a biotechnology company, engages in delivering genetic medicines to address the spectrum of diseases by deploying gene editing technology in the United States. Its lead therapeutic product candidate is PM359 for Chronic Granulomatous Disease, which is in Phase 1/2 clinical trial; PM577 for Wilson Disease, that is in preclinical studies; and PM647 to treat genetic disorder caused by mutations in the SERPINA1 gene, resulting in production of misfolded Z-AAT protein that accumulates in the liver and leads to hepatocellular injury, cirrhosis, and increased risk of hepatocellular carcinoma. The company also provides vivo programs targeting diseases of the liver, and Cystic Fibrosis programs. In addition, it offers Prime Editing technology comprising a programmable DNA binding domains, such as Cas domains, are typically modified such that they do not cause a double-stranded break in the DNA, as well as a RT domain that copies the edited DNA sequence directly into the target genomic site where the edit is made; and pegRNA which contains a search sequence, also known as a spacer, which provides a target genomic address for the Prime Editor. The company has a research collaboration and license agreement with BMS; Cystic Fibrosis Foundation; Broad Institute; and Beam. Prime Medicine, Inc. was incorporated in 2019 and is headquartered in Cambridge, Massachusetts.
Market information source · Oct 5, 2026
SEC company identity · Oct 5, 2026
Open-market timeline · full history
20 buys33 sells— close pricebar = usd volume, √ scaleclick a period to filter the table
| Insider | Type | Value · USD | Signals | Details |
|---|---|---|---|---|
| Cahill Thomas | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Chung Wendy | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Schenkein David P | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Foster-Cheek Kaye I | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Kelly Michael Aaron | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| NELSEN ROBERTtrack record | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Marrazzo Jeffrey D | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Makhni Svetlana Ni | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Reine Allan | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Alenson Carman | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| LEE ANN L. | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Kelly Michael Aaron | AwardD (derivative) | n/a (No price was disclosed in the filing) | SEC |
| Alenson Carman | AwardD (derivative) | n/a (No price was disclosed in the filing) | SEC |
| NELSEN ROBERTtrack record | OtherD (derivative) | n/a (No price was disclosed in the filing) | SEC |
| Marrazzo Jeffrey D | AwardD (derivative) | n/a (No price was disclosed in the filing) | SEC |
| Kelly Michael Aaron | OtherD (derivative) | n/a (No price was disclosed in the filing) | SEC |
| Alenson Carman | OtherD (derivative) | n/a (No price was disclosed in the filing) | SEC |
| Kelly Michael Aaron | OtherD (derivative) | n/a (No price was disclosed in the filing) | SEC |
| Alphabet Inc.track record | Buy | $5M | conv 73ClusterUnusual size+1 | SEC |
| Cahill Thomas | OtherD (derivative) | n/a (No price was disclosed in the filing) | SEC |
| Chung Wendy | OtherD (derivative) | n/a (No price was disclosed in the filing) | SEC |
| Foster-Cheek Kaye I | OtherD (derivative) | n/a (No price was disclosed in the filing) | SEC |
| NELSEN ROBERTtrack record | OtherD (derivative) | n/a (No price was disclosed in the filing) | SEC |
| Foster-Cheek Kaye I | AwardD (derivative) | n/a (No price was disclosed in the filing) | SEC |
| Kelly Michael Aaron | AwardD (derivative) | n/a (No price was disclosed in the filing) | SEC |