Figures computed from official regulatory filings — .
Analysttarget 4.38 USD (+180%) · consensus 4/5 · 4 buy · 2 hold · 0 sell
Ownershipinsiders 50.52% · institutions 27.56% · short 8.7% of float
In USD · as of Oct 5, 2026
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OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company operates in two segments, Pharmaceutical and Diagnostics. The Pharmaceutical segment develops MDX2001, a tetra-specific antibody targeting several types of solid tumors in Phase 1 clinical trials; MDX2003, a tetra-specific antibody targeting two antigens for hematological tumors in Phase 1 clinical trials; and MDX2004, a trispecific immune modulator to rebuild and sustain the patient's own immune system. This segment also engages in the development of Epstein Barr Virus vaccine; Rayaldee, a patented extended-release product for oral administration containing 30 mcg of a prohormone; OPK-88006 oral and injectable product to regulate blood glucose and reduce body weight; NGENLA, recombinant human growth hormone product developed for the long-term treatment of pediatric patients with growth hormone deficiency. The Diagnostics segment offers laboratory testing services, such as detection, diagnosis, evaluation, monitoring, and treatment of diseases, as well as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare under the BioReference brand; and 4Kscore test. OPKO Health, Inc. was founded in 2006 and is headquartered in Miami, Florida.
Market information source · Oct 5, 2026
Periods recorded in the consulted sources. These do not certify the legal dates of name changes.
SEC company identity · Oct 5, 2026
Open-market timeline · full history
12,319 buys42 sells— close pricebar = usd volume, √ scaleclick a period to filter the table
| Insider | Type | Value · USD | Signals | Details | |
|---|---|---|---|---|---|
| Rubin Steven Dtrack record | Other | $65K | SEC |
| Logal Adamtrack record | Other | $65K | SEC |
| PAGANELLI JOHN Atrack record | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Lachman Prem A | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Yu Alice Lin-Tsing | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| MEDEL ROGER MD | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| PFENNIGER RICHARD C JRtrack record | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| UPPALURI SUBBARAO Vtrack record | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| PAGANELLI JOHN Atrack record | Buy | $11.4K | conv 49First in 12mo | SEC |
| UPPALURI SUBBARAO Vtrack record | AwardD (derivative) | n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise)) | SEC |
| Frost Gamma Investment Trusttrack record | Buy | $133.1K | conv 39 | SEC |
| Frost Gamma Investment Trusttrack record | Buy | $254.7K | conv 50 | SEC |
| Frost Gamma Investment Trusttrack record | Buy | $258.4K | conv 50 | SEC |
| Frost Gamma Investment Trusttrack record | Buy | $5.1K | conv 35 | SEC |
| Frost Gamma Investment Trusttrack record | Buy | $118.9K | conv 38 | SEC |
| Frost Gamma Investment Trusttrack record | Buy | $2.4K | conv 35 | SEC |
| Frost Gamma Investment Trusttrack record | Buy | $216.8K | conv 49 | SEC |
| Frost Gamma Investment Trusttrack record | Buy | $281.9K | conv 55Unusual size | SEC |
| Frost Gamma Investment Trusttrack record | Buy | $62.6K | conv 35 | SEC |
| Frost Gamma Investment Trusttrack record | Buy | $32.9K | conv 35 | SEC |
| Frost Gamma Investment Trusttrack record | Buy | $18.4K | conv 35 | SEC |
| Frost Gamma Investment Trusttrack record | Buy | $157.3K | conv 43 | SEC |
| Frost Gamma Investment Trusttrack record | Buy | $87.1K | conv 36 | SEC |
| Frost Gamma Investment Trusttrack record | Buy | $205.3K | conv 45 | SEC |
| Frost Gamma Investment Trusttrack record | Buy | $39.1K | conv 35 | SEC |