Third Rock Ventures II, L.P.

10% owner at Sage Therapeutics, Inc. · on record since Jul 23, 2014
10% owner at Blueprint Medicines Corp · on record since Apr 29, 2015
10% owner at Global Blood Therapeutics, Inc. · on record since Aug 19, 2015
10% owner at MyoKardia, Inc. · on record since Oct 28, 2015
10% owner at Jounce Therapeutics, Inc. · on record since Jan 26, 2017
10% owner at Allena Pharmaceuticals, Inc. · on record since Nov 6, 2017
10% owner at Revolution Medicines, Inc. · on record since Feb 18, 2020

Insider trading activity of Third Rock Ventures II, L.P.

Transactions on record: 27; since Jan 20, 2015

Open-market buys: 1; $3M

Open-market sells: 5; $47.9M

Companies traded: 5; last filing Nov 6, 2017

Figures computed from official regulatory filings — .

Companies where Third Rock Ventures II, L.P. has traded

Allena Pharmaceuticals, Inc.4 tx · $3M · Nov 6, 2017
MyoKardia, Inc.8 tx · $9.1M · Sep 29, 2017
Global Blood Therapeutics, Inc.3 tx · $38.7M · Apr 6, 2017
Blueprint Medicines Corp6 tx · May 12, 2015
Sage Therapeutics, Inc.6 tx · Jan 28, 2015

Track record of Third Rock Ventures II, L.P.

Insufficient history for a statistical track record (fewer than 5 open-market buys).

Transaction history of Third Rock Ventures II, L.P.

Co-insiders of Third Rock Ventures II, L.P.

This page republishes public regulatory disclosures.

Company	Filed	Type	Qty	Price	Value · USD	Signals	Src
Allena Pharmaceuticals, Inc.Listing unverified	Nov 6, 2017	OtherD (derivative)	-4,629,630	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Allena Pharmaceuticals, Inc.Listing unverified	Nov 6, 2017	Other	2,575,964	—	n/a (No price was disclosed in the filing)		SEC
Allena Pharmaceuticals, Inc.Listing unverified	Nov 6, 2017	OtherD (derivative)	-6,122,448	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Allena Pharmaceuticals, Inc.Listing unverified	Nov 6, 2017	Buy	215,000	14.00 USD	$3M	conv 46ClusterFirst in 12mo	SEC
MyoKardia, Inc.Listing unverified	Sep 29, 2017	Other	-2,000,000	—	n/a (No price was disclosed in the filing)		SEC
MyoKardia, Inc.Listing unverified	Sep 12, 2017	Sell	-900	42.39 USD	$38.2K		SEC
MyoKardia, Inc.Listing unverified	Sep 12, 2017	Sell	-200,350	41.00 USD	$8.2M		SEC
MyoKardia, Inc.Listing unverified	Sep 12, 2017	Sell	-20,000	44.25 USD	$885K		SEC
Global Blood Therapeutics, Inc.Listing unverified	Apr 6, 2017	Other	-2,000,000	—	n/a (No price was disclosed in the filing)		SEC
Global Blood Therapeutics, Inc.Listing unverified	Nov 16, 2016	Sell	-1,000,000	19.36 USD	$19.4M		SEC
Global Blood Therapeutics, Inc.Listing unverified	Nov 16, 2016	Sell	-1,000,000	19.36 USD	$19.4M		SEC
MyoKardia, Inc.Listing unverified	Nov 5, 2015	OtherD (derivative)	-5,500,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
MyoKardia, Inc.Listing unverified	Nov 5, 2015	Other	8,843,537	—	n/a (No price was disclosed in the filing)		SEC
MyoKardia, Inc.Listing unverified	Nov 5, 2015	OtherD (derivative)	-32,500,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
MyoKardia, Inc.Listing unverified	Nov 5, 2015	Other	1,496,598	—	n/a (No price was disclosed in the filing)		SEC
Blueprint Medicines CorpListing unverified	May 12, 2015	OtherD (derivative)	-1,328,502	—	n/a (No price was disclosed in the filing)		SEC
Blueprint Medicines CorpListing unverified	May 12, 2015	OtherD (derivative)	-30,000,000	—	n/a (No price was disclosed in the filing)		SEC
Blueprint Medicines CorpListing unverified	May 12, 2015	Other	5,454,545	—	n/a (No price was disclosed in the filing)		SEC
Blueprint Medicines CorpListing unverified	May 12, 2015	Other	241,545	—	n/a (No price was disclosed in the filing)		SEC
Blueprint Medicines CorpListing unverified	May 12, 2015	Other	1,424,242	—	n/a (No price was disclosed in the filing)		SEC
Blueprint Medicines CorpListing unverified	May 12, 2015	OtherD (derivative)	-7,833,333	—	n/a (No price was disclosed in the filing)		SEC
Sage Therapeutics, Inc.Listing unverified	Jan 28, 2015	Other	-1,255,177	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Sage Therapeutics, Inc.Listing unverified	Jan 28, 2015	Other	81,094	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Sage Therapeutics, Inc.Listing unverified	Jan 28, 2015	Other	-81,094	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Sage Therapeutics, Inc.Listing unverified	Jan 20, 2015	Other	-652,758	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC

Company	Filed	Type	Qty	Price	Value · USD	Signals	Src
Allena Pharmaceuticals, Inc.Listing unverified	Nov 6, 2017	OtherD (derivative)	-4,629,630	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Allena Pharmaceuticals, Inc.Listing unverified	Nov 6, 2017	Other	2,575,964	—	n/a (No price was disclosed in the filing)		SEC
Allena Pharmaceuticals, Inc.Listing unverified	Nov 6, 2017	OtherD (derivative)	-6,122,448	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Allena Pharmaceuticals, Inc.Listing unverified	Nov 6, 2017	Buy	215,000	14.00 USD	$3M	conv 46ClusterFirst in 12mo	SEC
MyoKardia, Inc.Listing unverified	Sep 29, 2017	Other	-2,000,000	—	n/a (No price was disclosed in the filing)		SEC
MyoKardia, Inc.Listing unverified	Sep 12, 2017	Sell	-900	42.39 USD	$38.2K		SEC
MyoKardia, Inc.Listing unverified	Sep 12, 2017	Sell	-200,350	41.00 USD	$8.2M		SEC
MyoKardia, Inc.Listing unverified	Sep 12, 2017	Sell	-20,000	44.25 USD	$885K		SEC
Global Blood Therapeutics, Inc.Listing unverified	Apr 6, 2017	Other	-2,000,000	—	n/a (No price was disclosed in the filing)		SEC
Global Blood Therapeutics, Inc.Listing unverified	Nov 16, 2016	Sell	-1,000,000	19.36 USD	$19.4M		SEC
Global Blood Therapeutics, Inc.Listing unverified	Nov 16, 2016	Sell	-1,000,000	19.36 USD	$19.4M		SEC
MyoKardia, Inc.Listing unverified	Nov 5, 2015	OtherD (derivative)	-5,500,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
MyoKardia, Inc.Listing unverified	Nov 5, 2015	Other	8,843,537	—	n/a (No price was disclosed in the filing)		SEC
MyoKardia, Inc.Listing unverified	Nov 5, 2015	OtherD (derivative)	-32,500,000	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
MyoKardia, Inc.Listing unverified	Nov 5, 2015	Other	1,496,598	—	n/a (No price was disclosed in the filing)		SEC
Blueprint Medicines CorpListing unverified	May 12, 2015	OtherD (derivative)	-1,328,502	—	n/a (No price was disclosed in the filing)		SEC
Blueprint Medicines CorpListing unverified	May 12, 2015	OtherD (derivative)	-30,000,000	—	n/a (No price was disclosed in the filing)		SEC
Blueprint Medicines CorpListing unverified	May 12, 2015	Other	5,454,545	—	n/a (No price was disclosed in the filing)		SEC
Blueprint Medicines CorpListing unverified	May 12, 2015	Other	241,545	—	n/a (No price was disclosed in the filing)		SEC
Blueprint Medicines CorpListing unverified	May 12, 2015	Other	1,424,242	—	n/a (No price was disclosed in the filing)		SEC
Blueprint Medicines CorpListing unverified	May 12, 2015	OtherD (derivative)	-7,833,333	—	n/a (No price was disclosed in the filing)		SEC
Sage Therapeutics, Inc.Listing unverified	Jan 28, 2015	Other	-1,255,177	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Sage Therapeutics, Inc.Listing unverified	Jan 28, 2015	Other	81,094	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Sage Therapeutics, Inc.Listing unverified	Jan 28, 2015	Other	-81,094	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC
Sage Therapeutics, Inc.Listing unverified	Jan 20, 2015	Other	-652,758	0.00 USD	n/a (Non-cash transaction: the filing states a price of zero (award, gift, exercise))		SEC