Flagship Ventures Fund IV, L.P.

• 10% owner at Eleven Biotherapeutics, Inc. · on record since Feb 13, 2014
• 10% owner at T2 Biosystems, Inc. · on record since Aug 14, 2014
• 10% owner at Seres Therapeutics, Inc. · on record since Jun 29, 2015
• 10% owner at Editas Medicine, Inc. · on record since Feb 9, 2016
• 10% owner at Syros Pharmaceuticals, Inc. · on record since Jun 29, 2016
• 10% owner at EVOLVE ONE INC · on record since May 15, 2018
• 10% owner at Rubius Therapeutics, Inc. · on record since Jul 23, 2018
• 10% owner at NASTECH PHARMACEUTICAL CO INC · on record since Dec 13, 2018
• 10% owner at Kaleido Biosciences, Inc. · on record since Feb 27, 2019
• 10% owner at Axcella Health Inc. · on record since May 15, 2019
• 10% owner at TransMedics Group, Inc. · on record since May 6, 2019